Projects

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Current Projects

Genetic variants & Genotype-Phenotype correlation for primary angle closure glaucoma
Genetic Polymorphism as risk factors of Keratoconus among Egyptians
(Screening and Management plan for retinopathy (ROP)
Management of Allergic conjunctivitis and associated allergies
The progression of diabetic retinopathy in relation to the VEGF Angties system of angiogenic factors in human, potential treatment with angiotensin II inhibitors experimentally
Polyphenol liposomal nanoparticles of ocular applications
Prevention of blindness resulting from corneal opacities due to limbal stem cells deficiency or failure in Egypt

Recent Projects

RIO Program for Health Information Computerization and the Development of Electronic Health Record (HMIS) .

The project aims to

Prediction of diabetic retinopathy phenotype (Fluorescein FA classification) among Egyptian patients with type I diabetes and its genotype relation.
Detection of the value of new biochemical predictors of pre-proliferative stage of diabetic retinopathy among Egyptians
To investigate the genetic polymorphisms of sorbitol dehydrogenase (SDH) and vascular endothelial growth factor (VEGF) genes in Egyptian patients with types I diabetes mellitus and to assess their possible role as predictors for the development and progression of diabetic retinopathy.
To assess the incidence of the nephropathy, neuropathy and coronary heart disease in all diabetic patients participated in the project and correlate this with the stage of the retinopathy, biochemical results and to evaluate the role of genetic causes in the pathogenesis of these complications and their progression.
The project provides follow-up and family medical history, and a comprehensive medical examination and ECG analysis and a family pedigree. With conducting laboratory tests to measure Fasting & P.P. Blood glucose level, Total lipid profile, measuring kidney function, Glycated hemoglobin, special laboratory tests to predict the occurrence of diseases of the retina for a diabetic.
Prediction of diabetic retinopathy phenotype (Fluorescein FA classification) among Egyptian patients with type I diabetes and its genotype relation.
Detection of the value of new biochemical predictors of pre-proliferative stage of diabetic retinopathy among Egyptians
To investigate the genetic polymorphisms of sorbitol dehydrogenase (SDH) and vascular endothelial growth factor (VEGF) genes in Egyptian patients with types I diabetes mellitus and to assess their possible role as predictors for the development and progression of diabetic retinopathy.
To assess the incidence of the nephropathy, neuropathy and coronary heart disease in all diabetic patients participated in the project and correlate this with the stage of the retinopathy, biochemical results and to evaluate the role of genetic causes in the pathogenesis of these complications and their progression.

Evaluate the role of genetic causes in the pathogenesis of these complications and their progression

The project provides follow-up and family medical history, and a comprehensive medical examination and ECG analysis and a family pedigree. With conducting laboratory tests to measure Fasting & P.P. Blood glucose level, Total lipid profile, measuring kidney function, Glycated hemoglobin, special laboratory tests to predict the occurrence of diseases of the retina for a diabetic.
A polyclinic for diabetics (multidisciplinary) has been set up and provides full ophthalmologic examination, medical and genetics, as well as analyzes necessary medical and fundus fluorescein angiography, periodic follow-up, analysis and treatment to make sure to adjust the dose therapy and early intervention in case of any complications.
Also provides the place to turn to diabetics to receive appropriate care, which includes periodic follow-up for the eyes to reduce the risk of this disease in order to combat one of the most important causes of blindness. And follow the patient clinic for four years, and it scans the front and fundus examination using a slit lamp microscope, fundus fluorescein angiography and OCT.
It has been found that the proportion of patients with diabetic retinopathy, constituted 44% of patients with type I diabetes mellitus.

Previous Projects

2017

RIO Program for Prediction of Diabetic Retinopathy in Egyptian Patients with Type I Diabetes Mellitus.

2006

2009-2010

Screening of eye problems diseases among Rural Egyptian children aged one day to 6 years in Giza, 6 October & Helwan governorates project .

2006

(2002 -2006)

Exploratory study on the incidence of diabetic retinopathy among diabetic patients, that had been conducted in Research Institute of Ophthalmology Egyptian-Polish project.

2003

(1989-2003)

The effect of high-voltage electromagnetic fields, TV electromagnetic lines and radiation of computer monitors on the eye tissues.

1996

Epidemiological study on prevention of blindness in collaboration with WHO & Ministry of Health in the rural areas in El Ayatt and El-Saff, Giza

1994

1990-1994

A Study of common eye-diseases among primary-school children in Giza, Cairo, Monofia, Gharbia, Sharkia and Khalyobia governorates

1991

1989-1991

A survey study of common eye-diseases among patients attending rural health units in some villages of Giza Governorates

1988

1987-1988

In cooperation with the National Research Centre.

1984

1983-1984

General epidemiological studies of a statistical nature conducted in the following geographical areas: New Valley and several rural and semi-rural areas in Giza, Hurghada and the Red Sea

Book Chapter

Eman E.Taher– Mohamed Elalfy– KareemElsawah

Stem cell therapies in ocular repair, regeneration, and diseases

Research Institute of Ophthalmology, Giza, Egypt

Book Chapter

Nagwa Mostafa El-Sayed

Implications of Extracellular Vesicles in Blood Protozoan Parasitic Diseases

Medical Parasitology Department, Research Institute of Ophthalmology, Giza, Egypt

Springer Nature Singapore Pte Ltd. 2